Atypical-HUS is a difficult diagnosis to navigate, but the right information can help you and your patients
Explore disease state information and diagnostic tools.
Complement amplifying triggers can unmask atypical-HUS1,2
Atypical hemolytic uremic syndrome (atypical-HUS) is a rare, chronic disease characterized by uncontrolled activation of the complement system causing thrombotic microangiopathy (TMA) and organ damage.1,5 A number of triggers can amplify complement system activation and unmask underlying atypical-HUS.1,2
70% of patients (191/273) with atypical-HUS presented their first clinical manifestation while experiencing a trigger.3 Some examples of triggers include pregnancy or postpartum experiences, autoimmune disease, malignant hypertension, and organ transplantation. Understanding how patients may present with triggers can help to appropriately diagnose atypical-HUS as quickly as possible.4
LEARN ABOUT aHUS TRIGGERS